血液学および血栓塞栓性疾患ジャーナル
オープンアクセス
ISSN: 2329-8790
ISSN: 2329-8790
Aloy-Amadi Oluchi C, Ihekwoaba P, Nnodim Johnkennedy1*, Nwadike Constance N, Akujobi AU, Amilo GI
Background: Asthma is a condition in which a person’s airways become inflamed, narrow, swell and produce extra mucus which makes breathing difficult. It is a public health problem in all countries regardless of the level of development. In asthmatic condition, levels of some haematological parameters are altered.
Aim and objectives: The aim of this study was to determine the levels of some haematological parameters in asthmatic patients attending Imo State University Teaching Hospital, Orlu. The objectives includes: To determine the levels of Haemoglobin (Hb), White Blood Cell (WBC), platelets and differential WBC counts among asthmatic patients and non-asthmatic subjects.
Methodology: A cross-sectional study was carried out at Imo State University Teaching Hospital, Orlu from August- October, 2019. Fifty (50) asthmatic patients constituted the study population, while an equivalent number of apparently healthy age-matched individuals served as the controls. Questionnaires were administered to obtain their social and demographic data. Two milliliters (2 mls) of blood was collected from each individual and dispensed into potassium Ethylene Diamine Tetraacetic Acid (EDTA) containers for investigation of hematological parameters using haematology autoanalyzer. Data generated were analyzed using SPSS version 21.
Results: The mean values of WBC (× 109/l) (11.41 ± 1.77), neutrophils (%) (65.64 ± 7.97) and eosinophils (%) (5.76 ± 2.35) in the test groups were significantly raised when compared to the controls (4.88 ± 1.08), (57.28 ± 8.74) and (0.20 ± 0.50) respectively (p<0.001). That of Hb (g/dl) (10.60 ± 0.66) and lymphocytes (%) (27. ± 6.39) were significantly decreased in the study group compared to the control (11.85 ± 1.00) and (41.72 ± 7.72) (P<0.001), while the platelets in the test group (241.96 ± 55.69) were non-significantly increased when compared to the control (215.49 ± 43.13) (p=0.066). The level of monocytes in the study group (0.12 ± 0.44) showed no significant difference when compared to the control (0.016 ± 0.37) (p=0.731).
Conclusion: The findings have shown that some haematological parameters are altered in asthmatic condition. Therefore, these parameters should be included in the diagnosis of asthma for proper management of asthmatic patients.