リウマチ学: 現在の研究
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概要

Grown-up Beginning Still's Disease

Lei O

Grown-up beginning Still's disease (AOSD) is an uncommon fundamental fiery issue of obscure etiology, described by ordinary or double�?�quotidian spiking fevers with a transient rash, joint pain, and multiorgan inclusion. It owes its name to George Still who distributed in 1897 his monograph, On a type of ongoing joint infection in youngsters, depicting 22 kids with signs and manifestations of the illness element as of now known as foundational beginning adolescent idiopathic joint pain. In 1971, Eric Bywaters depicted 14 grown-ups with comparative introduction with pediatric Still's infection, convincingly building up the new sickness entity. However, the principal portrayal of a grown-up patient with signs and side effects of AOSD, wrongly marked rheumatoid joint inflammation, was distributed in the Lancet in 1896, one year before George Still's monograph. Since then numerous reports of fever of obscure root or "rheumatoid joint inflammation", which we would call AOSD, have showed up. In the French and German writing intermittent reports of AOSD are discovered, at that point called "subsepsis allergica" or "Wissler's disorder" and later the "Wissler�?� Fanconi syndrome".