薬物代謝と毒性学ジャーナル
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概要

A Brief Note on Drug Resistance

Esther Abam

The ineffectiveness of a treatment, such as an antibiotic or
antineoplastic, treating a disease or condition is known as drug
resistance. The phrase is used in the context of pathogen or
cancer resistance that has "acquired". Antimicrobial and
anticancer resistance provides a barrier to clinical care and
stimulates research.
Multidrug-resistant organisms are those that are resistant to
multiple drugs. Antibiotic resistance arises in part as a result of
medications that target just specific bacterial molecules. Any
alteration in these molecules will interfere with or nullify the
drug's destructive impact, resulting in antibiotic resistance. Drug,
toxin, and chemical resistance are result of evolution and a
reaction to the forces that each living thing faces. Individual
species differ in their susceptibility to the medicine, and those
with higher fitness may be able to withstand treatment. As a
result, drug-resistant features are passed down to following
generations, resulting in a population that is increasingly drugresistant.
Resistance to the medicine will certainly develop unless
the drug employed prevents sexual reproduction, cell division, or
horizontal gene transfer in the whole target population.