情報技術およびソフトウェア工学ジャーナル
オープンアクセス

概要

Effects of Lipoprotein (A) in Aortic Dissection Patients with Chest Pain and Healthy Groups: A Cross-Sectional Study

Hongliang Zhang

Background: Aortic dissection patients entering the hospital may suffer from chest pain and have a deviation value of lipoprotein (a) (Lp (a)). In the present study, we aimed to investigate the clinical importance of Lp (a) level among Aortic Dissection (AD) patients, healthy control.

Method: Fifty patients with acute Aortic Dissection (AD) and fifty healthy subjects were recruited in our current study. The baseline parameters of AD patients and control group were recorded, and the data were compared between the two groups. Receiver Operating Characteristic curve (ROC) was performed to assess the diagnostic ability of Lp (a), neutrophil/lymphocyte, CRP for the incidence of AD.

Results: The level of Lp (a), neutrophil/lymphocyte, CRP in AD was significantly higher than in the control group (P<0.05). ROC curve analysis showed that neutrophil, Lp (a), and neutrophil-lymphocyte ratio can distinguish AD patients from the control group.

Conclusions: This study indicates that Lp (a) can be evaluated as useful parameters in the emergency clinical approach in the evaluation of risk of acute aortic dissection. Future larger sample studies are required to confirm the results and address the role of these parameters in determining the severity of aortic dissection.