select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='11006' and ad.lang_id='6' and j.lang_id='6' and vi.lang_id='6' Elevated D-dimers without Disseminated Intravascular Coagula | 11006
リウマチ学: 現在の研究

リウマチ学: 現在の研究
オープンアクセス

ISSN: 2161-1149 (Printed)

概要

Elevated D-dimers without Disseminated Intravascular Coagulation in a Patient with Adult Onset Still’s Disease: An Indicator for Early Corticosteroid Treatment?

Natalia G Vallianou, Nikos Schizas, Angeliki Papanicolaou, Michalis Angelakos, George Katsikas and Evangelos Kokkinakis

Adult onset Still’s disease (AOSD), is an inflammatory disease characterized by fever, arthritis or arthralgias, muscle pain, pharyngitis, lymphadenopathy, rash and splenomegaly. Fever together with arthralgias and myalgias are reported in >90% of patients with AOSD. Disseminated intravascular coagulation is a very rare disorder, which may accompany severe cases of AOSD, especially in the context of hemophagocytic syndrome. Herein, we describe a patient with elevated d-dimers, but without disseminated intravascular coagulation and without hemophagocytic syndrome, who responded well to early corticosteroid treatment. We propose that isolated elevated d-dimers may be associated with the severity of the disease and may be suggestive of the need for early corticosteroid treatment.

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