Jonathan Rosenblum, David Friedman, Roslyn Rivkah Isseroff, Farzam Gorouhi
The authors evaluate a novel Surface Acoustic Wave (SAW) device as to its effect on epidermal health. The SAW device is indicated for use in phonophoresis as well as epidermal tissue growth in wound care. In order to understand the clinical effect the authors evaluate an in vitro skin model for SAW effect and examine the cellular and subcellular changes that occur with this device. CK17 proliferation, changes in GAG's (Glycosaminoglycans) and neoangiogenesis were positively affected by the SAW device.