肝臓学および胃腸疾患ジャーナル
オープンアクセス

概要

Malignant hyperthermia

Nidhin Eldo

Malignant hyperthermia is a pharmacogenetic disease triggered in susceptible individuals as a hypermetabolic response triggered by halogenated anaesthetics. The incidence of malignant hyperthermia is very less and the incidence occurring while on-going with renal transplant is considerably nil. The possibility of witnessing a malignant hyperthermia perioperative is a nightmare. The critical nature of the surgery and the on-going disease process in a paediatric patient makes it cumbersome and upon which a myoglobinemia, shock, and ischemia play a role in injuring the transplanted kidney.

Here we describe a 5 year old child diagnosed with posterior urethral vale and bilateral vesicouretric reflux has a non-functioning kidney and on-going with peritoneal dialysis, The patient has underwent multiple previous surgeries all under general anaesthesia without any complications.

This patient is posted for live related renal transplantation and right nephroureterectomy under general anaesthesia and develops dramatic changes in his hemodynamics and ventilatory parameters and  multiple challenges had to be tackled and was in a great dilemma whether to proceed, and how to proceed?

 We describe a case of malignant hyperthermia, its clinical course, and the measures taken to successfully treat it and preserve the function of a kidney allograft.

 

 

 

 

 

 

 

 

 

 16th World Nephrology Conference August 20-21, 2020 Webinar

 

    

Biography

Nidhin Eldo is doing his MRCP internal medicine training program at the age of 30 years from joint royal college of physicians training board UK.