細胞科学と治療のジャーナル
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概要

Molecular Modeling to Study Protein Function

Antoine de Morree

A protein’s structure and interactions are key to understanding its function. Skeletal muscle is filled with high molecular weight proteins that evade experimental determination of structure. Commonly, structures of single protein domains are used to overcome this hurdle. In addition, recent developments in molecular modeling enable solid testable predictions that further understanding of protein function.