物理化学および生物物理学ジャーナル

物理化学および生物物理学ジャーナル
オープンアクセス

ISSN: 2161-0398

概要

The Study of Novel Sulfilimines as Potential Insects Modulators

 Sha Zhou and Zhengming Li

This paper describes the novel sulfiliminyl structures as potential control of the Ca2+ influx within the Ryanodine Receptor of insect body. Referring to commercial Flubendiamide structural composition, N-cyano, N-trifluroacetyl and N-acylamino sulfiliminyl moieties were firstly introduced into dicarboxamides scaffolds. The chiral sulfilimines especially exhibited significant insecticidal activities. The investigation of chirality impact on bioactivity was also systemically studied.

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