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概要

Toxoplasmosis, a Common Neglected Disease of Disparity: Foodborne to Congenital complications and Novel Therapies

Helieh Saatara Oz

Toxoplasma causes a complex immune-inflammatory reaction in vital organs with the surge of chemokines and cytokines. Subsequent acute phase, the organisms lodge in cyst forms predominantly in muscles and adipose tissues and central nervous system for the life awaiting reactivation due to immunosuppression An estimated 1.5 billion people are predicted to be infected with Toxoplasma, an Apicomplexan organism. Toxoplasmosis is one of the most important foodborne illnesses, and inflammatory syndromes, as well as congenital disorders and hospitalization. Promiscuous Toxoplasma is transmitted by contaminated food and animal products, meat, milk and dairy (cysts form), water, fruits, vegetables (mainly oocysts), or sexually acquired through semen (tachyzoites). Toxoplasmosis is a neglected disease of poverty and prominent in rural areas according Center for Diseases Control.