臨床および実験皮膚科学研究ジャーナル
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概要

Xeroderma Pigmentosum with Acute Myeloid Leukemia and Meningiomas: Review of Literature

Nadia Zakir Mian, Pragya Kushwaha*

Xeroderma Pigmentosum (XP) a unique disorder, inherited as an autosomal recessive genodermatosis. Characterized by photosensitivity, freckly pigmented changes, premature skin ageing, telegiectasis, warty and papillomatous growth and malignant tumor development in later stage. Results from mutation in seven nucleotide excision repair gene (XPA to XP-G complement groups) and post replication repair defect (XP-Variant). This report aims to acknowledge the unique combination of XP along with neurological defects in a patient of acute myeloid leukemia.