クローニングと遺伝子導入
オープンアクセス

概要

Goats (Capra hircus) as Bioreactors for Production of Recombinant Proteins Interesting to Pharmaceutical Industry

Freitas VJF, Melo LM, Batista RITP, Souza-Fabjan JMG, Teixeira DIA, Serova IA, Andreeva LE, Burkov IA and Serov OL

Goats are a particularly efficient mean of producing recombinant proteins since they produce considerable amounts of milk, and incur lower investment and maintenance costs than cows. Thus, the aim of this review is to present the state-of-the-art for obtaining transgenic goats producing recombinant proteins for further utilization in the pharmaceutical industry. Additionally, the approaches to directed site-specific integration of transgene as well as the economic interest for this activity will be discussed.