select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='48307' and ad.lang_id='6' and j.lang_id='6' and vi.lang_id='6' The Role of T regulatory Cells (Tregs) in the Development an | 48307
音声学と聴覚学ジャーナル

音声学と聴覚学ジャーナル
オープンアクセス

ISSN: 2155-9899

概要

The Role of T regulatory Cells (Tregs) in the Development and Prevention of Type 1 Diabetes

Stavroula A. Paschou, Stelios Tigas, Katerina Naka, George K. Papadopoulos and Agathocles Tsatsoulis

In this article, we review the role of T regulatory cells (Tregs) in the development and prevention of type 1 diabetes. We first examine the definition of human Tregs, the generation of Tregs in the thymus and the periphery, their mode of action and their important role in the regulation of the immune response. We then examine the defects in Tregs observed thus far in type 1 diabetes and their role in the development of the disease. Finally, we point to possible clinical applications using Tregs as a therapeutic target for the prevention of type 1 diabetes.

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