血管学: オープンアクセス
オープンアクセス

概要

Usefulness of A-Lipoc Acid, Leucoselect and Ginkgoselect Phytosoma in Chronic Venous Insufficiency

Luca Costanzo, Antonino Grasso, Corrado Tamburino and Luigi Di Pino

Background: Chronic venous insufficiency (CVI) is a frequent pathology that affects quality of life of the patients due to several symptoms such as pain, leg cramps, aching and itch. Our scope was to verify the usefulness of a supplement based on α-lipoc acid, Leucoselect® and Ginkgoselect® phytosome in patients with CVI. Methods: From July to November 2015, 30 consecutive patients with CVI received once a day a tablet containing the supplement for a period of 4 weeks. A control group of 30 subjects taking placebo and matched for CVI class, age and sex was also recruited. Clinical evaluation using VCSS and microcirculatory assessment with perimalleolar capillaroscopy were performed. A questionnaire consisting of two questions investigating presence of pain and itch/ paraesthesia was also given to the patients. Each question was scored on a dichotomous Likert scale (0=no; 1=yes). Results: A significant reduction of VCSS from baseline to 4-weeks was observed in the group of treatment respect to control group (2.70 ± 0.95 vs 0.93 ± 0.74 and 2.87 ± 0.86 vs 2.60 ± 0.81, p