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概要

Lipid Spectrum of Membranes and Lipid Peroxidation and Proteins in the Liver Echinococcosis in Humans

Zanginyan H1*, Ghazaryan G1, Hovsepyan L1

One of the major issues in Medical Parasitology is Echinococcosis which causes the Hydatid disease of the liver. It causes significant useful changes in liver prompting to nearby entanglements related with liver disappointment and in addition loss of essentials of human body all in all. The weight of these cysts on liver tissue causes ischemia prompting to interruption of metabolic procedures in it. This is the reason why studies on revealing and improving dysfunctions in the mechanisms of oxygen-dependent processes allow to explain and adjust the characteristics of toxic liver damage in general. Study on these issue also allows to assists closely to the fundamental research in general biological problems, such as free radical oxygen and nitrogen species, peroxidase modification of lipids and proteins, function of biological membranes, etc. The consequences of our review demonstrate that LE causes profound practical changes with respect to the advancement of oxidative stress in the body. In perspective of the over, the increase and advancement of lipid peroxidation designs that we have found in LE pathogenesis procure a specific significance. Through our research we understand that hydatid ailment of the liver is because of initiation of free radical responses, which prompts to infringement of the digestion system of proteins and lipids in the structure of cell films, metabolic scatters showing a vital part of oxidative procedures in the pathogenesis of echinococcosis.