真菌のゲノミクスと生物学
オープンアクセス

概要

Preliminary Phytochemical Screening and Antimicrobial Activity of Salvadora persica Linn. Extracts against Oral Pathogens

Sanjay Kumar, Navneet, Shiv Shanker Gautam and Vinod Kumar

Salvadora persica Linn. is used traditionally as hypotensive, emollient, laxative, diuretic, febrifuge, skin cleanser and in treatment of urinary infections, gall stones, bronchial asthma and diarrhoea. The present study was designed for evaluation of phytochemical and anti-microbial aspects of S. persica stem and bark extracts against oral pathogens. The antimicrobial screening of extracts was examined by agar well diffusion method at 200 mg/ml sample concentration and minimum inhibitory concentrations (MICs) by two fold serial dilution method. Ofloxacin was used as positive control to determine the sensitivity of the strains. The results showed that MeOH extract was more active than other extracts in its antimicrobial activity ranged 14.0 ± 0.50-22.3 ± 0.76 mm respectively. MIC values were recorded between 3.12 to 25 mg/ml for all selected pathogens. Phytoconstituents analysis of plant extract revealed the presence of alkaloids, flavonoids, glycosides, steroids, tannins, terpenoids and saponins. The results corroborate the traditional uses of S. persica in treatment of dental diseases.