栄養と食品科学ジャーナル
オープンアクセス

概要

Tolerability Study of a Free Amino Acid-based Formula in Children with Cow's Milk Allergy

Jentzsch NS, Silveira FJF, Cruz LL, Wainstein APDL and Previato HDRA

Background: The prevalence of food allergy has increased worldwide. Cow’s milk allergy is a very common type of allergy in childhood. In non-breast-fed infants, with extremely severe or life-threatening symptoms, an amino acidbased formula may be considered the first choice for the dietary treatment. This study aimed to assess the tolerance to a new Brazilian amino acid-based formula and the nutritional status in children affected by cow’s milk allergy fed with this formula.

Objective: To assess the tolerance to an amino acid-based formula and its nutritional status impact on children affected by cow’s milk allergy.

Method: This is a clinical study conducted with a sample of 15 children, less than 5 years old with a clinical cow’s milk allergy diagnosis. The children were followed-up, in a Pediatric Outpatient Clinic. Anthropometric, clinical, epidemiological data were collected at the baseline and it was also prescribed the amino acid-based formula. Throughout the treatment, which lasted five months, the clinical response was assessed based on the remission of symptoms initially presented and the evolution of nutritional status, using the WHO child growth standards charts.

Results: The sample included predominantly boys with a mean age of 28.1 months and 66.7% IgE-mediated. The average age of onset of the allergic symptoms was 2.15 ± 2.33 months. Symptoms were reported in different systems (cutaneous, gastrointestinal and respiratory). In every child, there was complete remission of allergy symptoms initially presented and proper evolution of nutritional status.

Conclusion: This new free amino acid-based formula can safely be used for the dietary treatment for children with cow’s milk allergy. The subjects studied showed adequate children’s nutritional status evolution.